m-PEG7-Tos Chemical Properties

Boiling point:

535.8±50.0 °C(Predicted)

Density 

1.154±0.06 g/cm3(Predicted)

storage temp. 

Storage temp. 2-8°C

form 

Liquid

color 

Colorless to light yellow

m-PEG7-Tos Usage And Synthesis

Description

m-PEG7-Tos is a PEG linker containing a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Uses

m-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6

m-PEG7-Tos(155887-96-0)Related Product Information

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• m-PEG7-NHS ester
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• m-PEG7-Azide
• PEG7-Tos
• Hexaethylene glycol di(p-toluenesulfonate)