2-FLUOROPHENYLZINC IODIDE Chemical Properties

Boiling point:

65 °C

Density 

1.03 g/mL at 25 °C

Flash point:

1 °F

storage temp. 

2-8°C

Sensitive 

Air Sensitive

Exposure limits

ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)
OSHA: TWA 200 ppm(590 mg/m3)
NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)

Safety Information

Hazard Codes 

F,Xn

Risk Statements 

11-14-19-22-36/37/38-40-36/37

Safety Statements 

16-26-33-36/37

RIDADR 

UN 2056 3/PG 2

WGK Germany 

1

Hazard Note 

Flammable

HazardClass 

4.3

HS Code 

2827590000

MSDS

• Language:English Provider:SigmaAldrich

2-FLUOROPHENYLZINC IODIDE Usage And Synthesis

Application

2-Fluorophenyl zinc iodide is a pharmaceutical intermediate that has been reported in the literature to be used in the preparation of cannabinoid receptor modulators and estrogen receptor β (ERβ) agonists.

Application

2-Fluorophenyl zinc iodide can be used to prepare cannabinoid receptor modulators with the following structures. Currently recognized cannabinoid receptors include CB1 and CB2 receptors. In the early 1990s, CB1 and CB2 receptors, which bind to cannabinoids in vivo, were cloned, respectively. The CB1 receptor consists of 473 amino acids and 7 transmembrane domains, while the CB2 receptor consists of 360 amino acids and 7 transmembrane domains; both are G protein-coupled receptors. Cannabinoid receptor modulators have shown good therapeutic effects in treating multiple sclerosis, pain, and liver fibrosis.

2-FLUOROPHENYLZINC IODIDE(186000-41-9)Related Product Information

• 2-METHYLPHENYLZINC IODIDE
• 1-NAPHTHYLZINC IODIDE
• 2-(ETHOXYCARBONYL)PHENYLZINC BROMIDE
• 4-METHYLPHENYLZINC IODIDE
• 6-CHLOROHEXYLZINC BROMIDE
• 3-BROMOPHENYLZINC IODIDE
• 4-CHLORO-2-FLUOROPHENYLZINC IODIDE
• 4-bromo-2-fluorophenylzinc iodide solution,4-BROMO-2-FLUOROPHENYLZINC IODIDE, 0.5M,4-BROMO-2-FLUOROPHENYLZINC IODIDE
• 2-FLUOROPHENYLZINC IODIDE
• 4-BROMO-3-FLUOROPHENYLZINC IODIDE 0.5M&,4-bromo-3-fluorophenylzinc iodide solution
• 4-CHLORO-3-FLUOROPHENYLZINC IODIDE, 0.5M SOLUTION IN TETRAHYDROFURAN,4-CHLORO-3-FLUOROPHENYLZINC IODIDE,4-chloro-3-fluorophenylzinc iodide solution
• 3-chloro-4-fluorophenylzinc iodide solution,3-CHLORO-4-FLUOROPHENYLZINC IODIDE, 0.5M SOLUTION IN TETRAHYDROFURAN,3-CHLORO-4-FLUOROPHENYLZINC IODIDE
• 3-FLUOROPHENYLZINC IODIDE, 0.5M SOLUTION IN TETRAHYDROFURAN,3-fluorophenylzinc iodide solution,3-FLUOROPHENYLZINC IODIDE
• 2-CYANO-3-FLUOROPHENYLZINC IODIDE
• 2-CHLORO-4-FLUOROPHENYLZINC IODIDE
• 4-BROMO-3-FLUOROPHENYLZINC IODIDE
• 4-Chloro-2-fluorophenylzinc iodide 0.5M solution in THF
• 2-Cyano-3-fluorophenylzinc iodide 0.5M solution in THF