3'-Deoxy-3'-fluoro-N6,N6-dimethyladenosine
3'-Deoxy-3'-fluoro-N6,N6-dimethyladenosine Basic information
- Product Name:
- 3'-Deoxy-3'-fluoro-N6,N6-dimethyladenosine
- Synonyms:
-
- 3'-Deoxy-3'-fluoro-N6,N6-dimethyladenosine
- 3'-Deoxy-N6-dimethyl-3'-fluoroadenosine
- Adenosine, 3'-deoxy-3'-fluoro-N,N-dimethyl- (9CI)
- (2R,3S,4S,5R)-2-(6-(dimethylamino)-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
- CAS:
- 122654-28-8
- MF:
- C12H16FN5O3
- MW:
- 297.29
- Mol File:
- 122654-28-8.mol
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3'-Deoxy-3'-fluoro-N6,N6-dimethyladenosine Chemical Properties
- Boiling point:
- 567.8±60.0 °C(Predicted)
- Density
- 1.66±0.1 g/cm3(Predicted)
- pka
- 12.44±0.70(Predicted)
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3'-Deoxy-3'-fluoro-N6,N6-dimethyladenosine Usage And Synthesis
Uses
3’-Deoxy-3’-fluoro-N6,N6-dimethyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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