18031153937@189.cn
18031153937@189.cn Basic information
- Product Name:
- 18031153937@189.cn
- Synonyms:
-
- 1-(5-chloro-1H-indol-3-yl)propan-2-amine
- 5-chloro AMT
- 5-Chloro-α-methyltryptamine
- CAS:
- 712-07-2
- MF:
- C11H13ClN2
- MW:
- 208.68732
- Mol File:
- 712-07-2.mol
More
Less
18031153937@189.cn Chemical Properties
- solubility
- DMF: 5 mg/ml; DMSO: 16 mg/ml; Ethanol: 14 mg/ml; PBS (pH 7.2): insol
- form
- A crystalline solid
More
Less
18031153937@189.cn Usage And Synthesis
Uses
5-Chloro-α-methyltryptamine (Compound 7b) is a potent and selective dual DA/5-HT releaser and 5-HT2a agonist. 5-Chloro-α-methyltryptamine releases DA and 5-HT with the EC50 values of 54.3 nM and 16.2 nM, respectively. 5-Chloro-α-methyltryptamine can be used in the study of neurotransmitter[1].
IC 50
5-HT2A Receptor
References
[1] Blough BE, et al. Alpha-ethyltryptamines as dual dopamine-serotonin releasers. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4754-4758. DOI:10.1016/j.bmcl.2014.07.062