Bedaquiline (1S,2S) Isomer Impurity 3 Chemical Properties

Boiling point:

702.7±60.0 °C(Predicted)

Density 

1.322±0.06 g/cm3(Predicted)

solubility 

Chloroform (Slightly, Sonicated), Methanol (Slightly, Heated)

pka

13.05±0.29(Predicted)

form 

Solid

color 

White to Off-White

Bedaquiline (1S,2S) Isomer Impurity 3 Usage And Synthesis

Uses

(aS,bS)-rel-Bedaquiline-d6 is an enantiomer separated in the synthesis of Bedaquiline-d6 (Mixture of Diastereomers) (B119552) which is the labelled analog of Bedaquiline, a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.