Flunarizine EP Impurity C Chemical Properties

Melting point:

>212°C (dec.)

Boiling point:

507.9±50.0 °C(Predicted)

Density 

1.170±0.06 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Acetonitrile (Slightly, Heated), DMSO (Slightly), Methanol (Sparingly)

form 

Solid

pka

6.94±0.10(Predicted)

color 

White to Off-White

Stability:

Hygroscopic

Flunarizine EP Impurity C Usage And Synthesis

Uses

4-Defluoro 2-Fluoro Flunarizine Dihydrochloride is an impurity of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral).