DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE Chemical Properties

Melting point:

105-108 °C(lit.)

Boiling point:

372.6±37.0 °C(Predicted)

Density 

1.3137 (rough estimate)

refractive index 

1.5500 (estimate)

pka

-0.53±0.10(Predicted)

form 

Crystalline Powder

color 

Slightly yellow to beige-yellow

CAS DataBase Reference

4815-30-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-60-37

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE Usage And Synthesis

Chemical Properties

slightly yellow to beige-yellow crystalline powder

Uses

Diethyl 5-Amino-3-methylthiophene-2,4-dicarboxylate is used as a reagent in the synthesis of novel pyrazolo-pyrimidinones as dipeptidyl peptidase IV (DPP-IV) inhibitors in diabetes. It is also used in the synthesis of N-phenylthieno[2,3-d]pyrimidin-4-amines which act as inhibitors of fibroblast grow factor receptor 1 and therefore may be further used as anticancer agents.

DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE(4815-30-9)Related Product Information

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