1-pyridin-4-yl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
1-pyridin-4-yl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one Basic information
- Product Name:
- 1-pyridin-4-yl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
- Synonyms:
-
- 1-pyridin-4-yl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
- 3-(3,4,5-TRIMETHOXYPHENYL)-1-(PYRIDIN-4-YL)PROP-2-EN-1-ONE
- 2-Propen-1-one, 1-(4-pyridinyl)-3-(3,4,5-trimethoxyphenyl)-
- CYP1A1 inhibitor 8a
- CYP1A1 inhibitor 8a,CYP-1A1 inhibitor 8a
- CAS:
- 159429-58-0
- MF:
- C17H17NO4
- MW:
- 299.32
- Mol File:
- 159429-58-0.mol
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1-pyridin-4-yl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one Chemical Properties
- Melting point:
- 194-196 °C(Solv: methanol (67-56-1); ethanol (64-17-5))
- Boiling point:
- 468.8±45.0 °C(Predicted)
- Density
- 1.173±0.06 g/cm3(Predicted)
- pka
- 2.84±0.10(Predicted)
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1-pyridin-4-yl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one Usage And Synthesis
Description
CYP1A1 inhibitor 8a is a potent and selective CYP1A1 inhibitor. It acts by antagonizing B[a]P mediated activation of aromatic hydrocarbon receptor (AhR) in yeast cells and protecting human cells from CYP1A1-mediated B[a]P toxicity.
1-pyridin-4-yl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneSupplier
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