NERVONIC CERAMIDE
NERVONIC CERAMIDE Basic information
- Product Name:
- NERVONIC CERAMIDE
- Synonyms:
-
- 15-TETRACOSENAMIDE
- NERVONIC CERAMIDE
- NERVONYL CERAMIDE
- NERVONYL-D-SPHINGOSINE
- N-[CIS-TETRACOSENOYL]-D-SPHINGOSINE
- N-15Z-TETRACOSENOYLSPHINGOSINE
- N-nervonoyl-D-sphingosine
- Nervonyl Ceramide, N-[cis-Tetracosenoyl]-D-sphingosine
- CAS:
- 54164-50-0
- MF:
- C42H81NO3
- MW:
- 648.1
- Product Categories:
-
- Mixed Fatty Acids
- Activators
- Fatty Acid Derivatives & Lipids
- Glycerols
- Inhibitors
- Protein Kinase Inhibitors and Activators
- Mol File:
- 54164-50-0.mol
NERVONIC CERAMIDE Chemical Properties
- Melting point:
- 80-82°C
- storage temp.
- -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- color
- Off-White
NERVONIC CERAMIDE Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
N-Nervonoyl-D-sphingosine is a sphingolipid. Sphingolipids (SLs) act as signaling molecules and as structural components in both neuronal cells and myelin.
Uses
Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of phospholipase C, appropriately named sphingomyelinase.
Definition
ChEBI: N-(15Z)-tetracosenoylsphingosine is an N-tetracosenoylsphingosine in which the double bond in the ceramide acyl group is located at position 15 (the Z-geoisomer. It has a role as a mouse metabolite. It is a N-tetracosenoylsphingosine and a Cer(d42:2). It is functionally related to a (15Z)-tetracosenoic acid.
Biological Activity
Ceramide (d18:1/24:1[15Z]) levels are elevated inprimary open angle glaucoma (POAG). It is a biomarker for the human arterial tissue and plasma major adverse cardiac and cerebrovascular events (MACE). In general, ceramides are key second messengers in sphingomyelin pathway and modulate the pathophysiology of metabolic diseases.
NERVONIC CERAMIDESupplier
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