Ethyl pyrazole-3-carboxylate Chemical Properties

Melting point:

158-160 °C

Boiling point:

279 °C

Density 

1.214

Flash point:

123 °C

storage temp. 

Inert atmosphere,Room Temperature

form 

powder

pka

11.04±0.10(Predicted)

color 

yellowish-orange

InChI

InChI=1S/C6H8N2O2/c1-2-10-6(9)5-3-4-7-8-5/h3-4H,2H2,1H3,(H,7,8)

InChIKey

MSPOSRHJXMILNK-UHFFFAOYSA-N

SMILES

N1C=CC(C(OCC)=O)=N1

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

TSCA 

No

HazardClass 

IRRITANT

HS Code 

2933199090

Ethyl pyrazole-3-carboxylate Usage And Synthesis

Synthesis

Pyrazole-3-carboxylic acid (1.112 g, 10 mmol) was dissolved in ethanol (50 mL) at 80 °C, followed by slow addition of concentrated sulfuric acid (2 mL). The reaction mixture was kept under stirring for 2 hours. Upon completion of the reaction, ethyl 1H-pyrazole-3-carboxylate (1.350 g, 9.6 mmol, 96% yield) was obtained.

References

[1] Journal of the Iranian Chemical Society, 2016, vol. 13, # 5, p. 823 - 830
[2] Patent: US9206115, 2015, B2. Location in patent: Page/Page column 25-26
[3] Patent: EP3235819, 2017, A1. Location in patent: Paragraph 0264; 0265
[4] Journal of the American Chemical Society, 2000, vol. 122, # 44, p. 10810 - 10820
[5] Patent: WO2008/92942, 2008, A2. Location in patent: Page/Page column 20

Ethyl pyrazole-3-carboxylate(5932-27-4)Related Product Information

• Benzocaine
• Pyrazole
• ISOXADIFEN-ETHYL
• Zolpidem tartrate
• Pyraclostrobin
• Ethyl acetate
• Trinexapac-ethyl
• Urethane
• N-Carbobenzyloxyglycine
• Ethyl acrylate
• Ethyl cyanoacetate
• Ethanol
• Ethyl formate
• 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one
• RESMETHRIN
• Triethyl orthoformate
• Ethyl cyanoformate
• Ethylparaben