4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride Chemical Properties

Boiling point:

360.9±42.0 °C(Predicted)

Density 

1.42±0.1 g/cm3(Predicted)

storage temp. 

-20°C

form 

powder or crystals

4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride Usage And Synthesis

Uses

Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.