(ASP371)-TYROSINASE (369-377) (HUMAN) Chemical Properties

Boiling point:

1578.2±65.0 °C(Predicted)

Density 

1.375±0.06 g/cm3(Predicted)

storage temp. 

-15°C

solubility 

deionized water: soluble

form 

lyophilized powder

pka

3.32±0.10(Predicted)

color 

white

Sequence

Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val

Safety Information

WGK Germany 

3

(ASP371)-TYROSINASE (369-377) (HUMAN) Usage And Synthesis

Uses

Tyrosinase 369-377, human is a HLA-A2.1-restricted epitope derived from tyrosinase, has been used to develop tumor-targeted vaccines with mixed efficacy[1][2].

References

[1] Guillaume B, et al. Analysis of the processing of seven human tumor antigens by intermediate proteasomes. J Immunol. 2012 Oct 1;189(7):3538-47. DOI:10.4049/jimmunol.1103213
[2] Mitchell MS, et al. Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. J Clin Oncol. 2002 Feb 15;20(4):1075-86. DOI:10.1200/JCO.2002.20.4.1075

(ASP371)-TYROSINASE (369-377) (HUMAN)(168650-46-2)Related Product Information

• H-LYS-CYS-ASP-ILE-CYS-THR-ASP-GLU-TYR-OH
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• TYROSINASE (206-214) (HUMAN)