METHYL 8-CHLORO-8-OXOOCTANOATE Chemical Properties

Density 

1.456 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.45(lit.)

Flash point:

>230 °F

solubility 

Chloroform, Ethyl Acetate (Slightly)

form 

Oil

color 

Clear Colourless to Pale Yellow

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

23-26-27-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

HazardClass 

6.1(a)

PackingGroup 

II

MSDS

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METHYL 8-CHLORO-8-OXOOCTANOATE Usage And Synthesis

Uses

Methyl 8-Chloro-8-oxooctanoate is used as a reagent in the synthesis of b-cyclodextrin-6-deoxy-6-NHC(O)(CH2)6C(O)NHOH which is a b-cyclodextrin-capped histone deacetylase inhibitor that may have potential for use in treatment of cancers and inflammatory diseases. It is also used in one synthetic route for tubacin which is a known anticancer agent.

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