Lalistat 2
Lalistat 2 Basic information
- Product Name:
- Lalistat 2
- Synonyms:
-
- Lalistat 2
- 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate
- Lalistat 2 >=98% (HPLC)
- lysosomal acid lipase deficiency,dried blood spot,Lalistat2,Lalistat-2,Inhibitor,cholesteryl ester storage disease,Lalistat 2,inhibit
- 1-Piperidinecarboxylic acid, 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester
- Lalistat 2, 10 mM in DMSO
- CAS:
- 1234569-09-5
- MF:
- C13H20N4O2S
- MW:
- 296.39
- Mol File:
- 1234569-09-5.mol
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Lalistat 2 Chemical Properties
- Boiling point:
- 438.5±45.0 °C(Predicted)
- Density
- 1.295±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.16 mg/ml
- form
- A crystalline solid
- pka
- 5.53±0.10(Predicted)
- color
- White to off-white
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Lalistat 2 Usage And Synthesis
Uses
Lalistat 2 is used in the synthetic preparation of thiadiazole carbamates as inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics.
Biological Activity
Lalistat-2 is a potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa). Lalistat-2 affects lipid droplets morphology and localization.
storage
Store at +4°C
Lalistat 2Supplier
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