proTAME
proTAME Basic information
- Product Name:
- proTAME
- Synonyms:
-
- proTAME
- pro-Tosyl-L-Arginine Methyl Ester
- 10,12-Dioxa-6,8-diazatetradec-6-enoic acid, 2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-, methyl ester, (2S)-
- (2S)-2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-10,12-dioxa-6,8-diazatetradec-6-enoicacid,methylester
- CAS:
- 1362911-19-0
- MF:
- C34H38N4O12S
- MW:
- 726.75
- Mol File:
- 1362911-19-0.mol
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proTAME Chemical Properties
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: Soluble
- pka
- 7.05±0.46(Predicted)
- form
- Solid
- color
- White to off-white
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proTAME Usage And Synthesis
Description
ProTAME is an inhibitor of both APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, etoposide and doxorubicin, significantly increase cell death in Multiple Myeloma (MM) cell lines and primary cells, particularly if TOPIIα levels are first increased through pre-treatment with ProTAME.
proTAMESupplier
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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- 17702719238 17702719238
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BOC Sciences
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- 1-631-485-4226; 16314854226
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Shanghai EFE Biological Technology Co., Ltd.
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- 021-65675885 18964387627
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Shanghai Hongye Biotechnology Co. Ltd
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- 400-9205774
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TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com