proTAME
proTAME Basic information
- Product Name:
- proTAME
- Synonyms:
-
- proTAME
- pro-Tosyl-L-Arginine Methyl Ester
- 10,12-Dioxa-6,8-diazatetradec-6-enoic acid, 2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-, methyl ester, (2S)-
- (2S)-2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-10,12-dioxa-6,8-diazatetradec-6-enoicacid,methylester
- CAS:
- 1362911-19-0
- MF:
- C34H38N4O12S
- MW:
- 726.75
- Mol File:
- 1362911-19-0.mol
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proTAME Chemical Properties
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: Soluble
- pka
- 7.05±0.46(Predicted)
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proTAME Usage And Synthesis
Description
ProTAME is an inhibitor of both APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, etoposide and doxorubicin, significantly increase cell death in Multiple Myeloma (MM) cell lines and primary cells, particularly if TOPIIα levels are first increased through pre-treatment with ProTAME.
proTAMESupplier
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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BOC Sciences
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- 1-631-485-4226; 16314854226
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Shanghai Hongye Biotechnology Co. Ltd
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- 400-9205774
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TargetMol Chemicals Inc.
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- +1-781-999-5354 +1-00000000000
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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- 86-571-88216897,88216896 13588875226
- sales@hzclap.com