AZD 3241
AZD 3241 Basic information
- Product Name:
- AZD 3241
- Synonyms:
-
- AZD 3241
- AZD3241;AZD-3241;AZD 3241
- Verdiperstat (Synonyms: AZD3241)
- Verdiperstat
- AZD 3241; VERDIPERSTAT
- 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1,2,3,5-tetrahydro-1-[2-(1-methylethoxy)ethyl]-2-thioxo-
- AZD3242
- Verdiperstat (AZD3241)
- CAS:
- 890655-80-8
- MF:
- C11H15N3O2S
- MW:
- 253.32
- EINECS:
- 682-454-5
- Mol File:
- 890655-80-8.mol
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AZD 3241 Chemical Properties
- Density
- 1.34±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 10 mg/mL; DMSO: 10 mg/mL; Ethanol: 2 mg/mL
- form
- A solid
- pka
- 8.25±0.20(Predicted)
- color
- White to light brown
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AZD 3241 Usage And Synthesis
Uses
Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
References
[1] Johnstr?m P, et al. Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing. Nucl Med Biol. 2015 Jun;42(6):555-60. DOI:10.1016/j.nucmedbio.2015.02.001
[2] Jucaite A, et al. Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease. Brain. 2015 Sep;138(Pt 9):2687-700. DOI:10.1093/brain/awv184
AZD 3241Supplier
Shanghai CanSpecsci Instrument Co., Ltd.
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- 400-6087598 15021221957
- order@canspecsci.com
Shanghai JiYi Biotechnology Co. Ltd.
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- 13621943973
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Shanghai YuanYe Biotechnology Co., Ltd.
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- 021-61312847; 18021002903
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ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
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Shanghai Chaolan Chemical Technology Center
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- Sales@ATKchemical.com