Dihydrochlamydocin
Dihydrochlamydocin Basic information
- Product Name:
- Dihydrochlamydocin
- Synonyms:
-
- Cyclo[2-methylalanyl-L-phenylalanyl-D-prolyl-(αS,ηS)-α-amino-η-hydroxyoxiraneoctanoyl] (9CI)
- Dihydrochlamydocin, Putative HDAC inhibitor
- CAS:
- 52574-64-8
- MF:
- C28H40N4O6
- MW:
- 528.65
- Mol File:
- 52574-64-8.mol
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Dihydrochlamydocin Chemical Properties
- Boiling point:
- 863.3±65.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- pka
- 13.37±0.70(Predicted)
- form
- solid
- color
- Off-white
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Dihydrochlamydocin Usage And Synthesis
Uses
Dihydrochlamydocin is a histone deacetylases (HDAC) inhibitor. Dihydrochlamydocin shows strong cytostatic activity towards mastocytoma cells[1].
Biological Activity
Phytotoxin. Derivative of the HDAC inhibitor chlamydocin.
storage
+4°C
References
[1] Degenkolb T, et al. Metabolites from nematophagous fungi and nematicidal natural products from fungi as an alternative for biological control. Part I: metabolites from nematophagous ascomycetes. Appl Microbiol Biotechnol. 2016;100(9):3799-3812. DOI:10.1007/s00253-015-7233-6