CINCHONINE MONOHYDROCHLORIDE HYDRATE
CINCHONINE MONOHYDROCHLORIDE HYDRATE Basic information
- Product Name:
- CINCHONINE MONOHYDROCHLORIDE HYDRATE
- Synonyms:
-
- CINCHONINE MONOHYDROCHLORIDE HYDRATE
- CAS:
- 206986-88-1
- MF:
- C19H25ClN2O2
- MW:
- 348.87
- EINECS:
- 635-464-9
- Mol File:
- Mol File
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CINCHONINE MONOHYDROCHLORIDE HYDRATE Chemical Properties
- Melting point:
- 208-218 °C(lit.)
- solubility
- soluble in Ethanol
- form
- powder to crystal
- color
- White to Almost white
- optical activity
- [α]20/D +101°, c = 1 in chloroform
- BRN
- 5784953
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MSDS
- Language:English Provider:SigmaAldrich
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CINCHONINE MONOHYDROCHLORIDE HYDRATE Usage And Synthesis
Uses
Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis[1].
References
[1] Jin ZL, et, al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050. DOI:10.3892/etm.2018.6005
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