Basic information Safety Supplier Related

ENDOTHAL

Basic information Safety Supplier Related

ENDOTHAL Basic information

Product Name:
ENDOTHAL
Synonyms:
  • 1,2-Benzenedicarboxylic acid, hexahydro-3,6-endo-oxy-
  • 1,2-Cyclohexanedicarboxylic acid, 3,6-endo-epoxy-
  • 3,6-endo-epoxy-2-cyclohexanedicarboxylicacid
  • 3,6-endo-Oxohexahydrophthalic acid
  • 3,6-endooxohexahydrophthalicacid
  • 3,6-endo-Oxyphthalic acid hexahydro-
  • 3,6-Endoxohexahydrophthalic acid
  • hexahydro-3,6-endo-oxy-2-benzenedicarboxylicacid
CAS:
145-73-3
MF:
C8H10O5
MW:
186.16
EINECS:
205-660-5
Product Categories:
  • Monoterpenoids
  • Inhibitors
Mol File:
145-73-3.mol
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ENDOTHAL Chemical Properties

Melting point:
179-180℃
Boiling point:
447.8±40.0 °C(Predicted)
Density 
1.431 g/cm3
storage temp. 
+2C to +8C
solubility 
DMF: 15 mg/ml,DMSO: 15 mg/ml,Ethanol: 15 mg/ml,PBS (pH 7.2): 0.2 mg/ml
form 
White solid
pka
3.62±0.40(Predicted)
color 
White to off-white
Water Solubility 
Soluble in water (>25 mg/ml), methanol, acetone, and DMSO. Insoluble in benzene.
Stability:
Hygroscopic
CAS DataBase Reference
145-73-3(CAS DataBase Reference)
EPA Substance Registry System
Endothall (145-73-3)
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Safety Information

Hazard Codes 
T
Risk Statements 
21-25-36/37/38
Safety Statements 
36/37/39-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
1
RTECS 
RN7875000
HazardClass 
6.1(a)
PackingGroup 
II
Hazardous Substances Data
145-73-3(Hazardous Substances Data)
Toxicity
LD50 in adult male, female rats (mg/kg): 57, 46 orally (Gaines, Linder)

MSDS

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ENDOTHAL Usage And Synthesis

Chemical Properties

Endothall, when pure, is a white crystalline solid. The technical grade is a light brown liquid

Uses

Defoliant, herbicide.

Uses

Preemergence and postemergence herbicide for control of broad-leaved weeds and annual grass in vegetable crops. The disodium and dipotassium salts are used as defoliants and herbicides.

Uses

Endothall is used as an inhibitor of PP2A phosphatase activity. It is also used as a defoliant. It is used as a cell adhesion inhibitor.

General Description

The monohydrate is in the form of colorless crystals. Non corrosive. Used as a selective herbicide.

Air & Water Reactions

Stable up to 90°C, above which ENDOTHAL undergoes slow hydrolysis.

Reactivity Profile

A phthalic acid derivative.

Hazard

Strong irritant to eyes and skin.

Agricultural Uses

Herbicide, Algaecide: Endothall is used as a cotton defoliant and as a selective contact herbicide on both terrestrial and aquatic weeds. The potassium and amine salts of endothall are used as aquatic herbicides to control a variety of plants including plankton, pondweed, niad, coontail, milfoil, elodea, and algaes in water bodies and rice fields. Endothall is also used to control annual grass and broadleaf weeds in sugar beets, spinach and turf. It reduces sucker branch growth in hops. Endothall is a desiccant to aid the harvest of alfalfa, potatoes, clover, and cotton. Not approved for use in EU countries. Approved for use in the U.S. and other countries. There are 24 global suppliers.

Trade name

ACCELERATE®; AQUATHOL®; DES-I-CATE®; HYDOUT®; HYDROTHAL-47®; HYDROTHOL®; NIAGARATHOL®; RIPENTHOL®; TRI-ENDOTHAL®

Safety Profile

Poison by ingestion. Very irritating to skin, eyes, and mucous membranes. Causes dlarrhea. When heatedto decomposition it emits acrid smoke and fumes

Potential Exposure

Endothall is dicarboxylic acid defoliant and herbicide used on both terrestrial and aquatic weeds.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least

Environmental Fate

Biological. Incubation of 14C-ring labeled endothall (10 mg/mL) by Arthrobacter sp., which was isolated from pond water and a hydrosol, in aerobic sediment-water suspensions revealed that after 30 days, 40% evolved as 14CO2. Glutamic acid was the major transformation product. Minor products were alanine, citric and aspartic acids and unidentified products, some of which were tentatively identified as phosphate esters (Sikka and Saxena, 1973). In pond water treated with endothall (2 and 4 ppm), detectable levels were found after 7 days (Sikka and Rice, 1973). Biodegradation was rapid in an Ontario soil sample. After 1 week, 70% of endothall added was converted to carbon dioxide (Simsiman et al., 1976).
Chemical/Physical. Reacts with bases forming water-soluble salts. Above 90°C, endothall is slowly converted to the anhydride (Windholz et al., 1983; Hartley and Kidd, 1987) and water (Humburg et al., 1989). Endothall is stable to light (Hartley and Kidd, 1987).

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2588 Pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic, and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur)

Waste Disposal

Small quantities may be disposed of by burial in soil which is rich in organic matter. Large quantities are best disposed of by incineration. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (5100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office

ENDOTHALSupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Email
cdhxsj@163.com
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Email
800078821@qq.com
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Email
tauto@tautobiotech.com
Clearsynth Labs Limited
Tel
+91-22-26355700
Email
info@clearsynth.com