5'-Deoxy-5'-N,N-dimethylamino thymidine
5'-Deoxy-5'-N,N-dimethylamino thymidine Basic information
- Product Name:
- 5'-Deoxy-5'-N,N-dimethylamino thymidine
- Synonyms:
-
- 5'-Deoxy-5'-N,N-dimethylamino thymidine
- Thymidine, 5'-deoxy-5'-(dimethylamino)- (9CI)
- 5’-Deoxy-5’-N,N-dimethylaminothymidine
- CAS:
- 162466-79-7
- MF:
- C12H19N3O4
- MW:
- 269.3
- Mol File:
- 162466-79-7.mol
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5'-Deoxy-5'-N,N-dimethylamino thymidine Chemical Properties
- Density
- 1.285±0.06 g/cm3(Predicted)
- pka
- 9.55±0.10(Predicted)
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5'-Deoxy-5'-N,N-dimethylamino thymidine Usage And Synthesis
Uses
5’-Deoxy-5’-N,N-dimethylamino thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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