2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide Chemical Properties

Boiling point:

631.4±55.0 °C(Predicted)

Density 

1.211±0.06 g/cm3(Predicted)

storage temp. 

Room Temperature

solubility 

Chloroform, Dichloromethane, Dimethylsulfoxide, Methanol

pka

11.49±0.59(Predicted)

2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide Usage And Synthesis

Uses

3-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide is an intermediate in the synthesis of 3-Fluoro Atorvastatin Sodium Salt (F587915). 3-Fluoro Atorvastatin Sodium Salt is an impurity of Atorvastatin (A791750, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and the only drug in its class specifically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.