Basic information Safety Supplier Related

2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide

Basic information Safety Supplier Related

2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide Basic information

Product Name:
2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide
Synonyms:
  • 2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide
  • 3-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide
  • 3-Fluoro-a-(2-methyl-1-oxopropyl)--oxo-N,-diphenyl-benzenebutanamide
  • 3-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide
  • Benzenebutanamide, 3-fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-
  • Atorvastatin Impurity 159
  • Atorvastatin calcium impurity 80
CAS:
1817798-20-1
MF:
C26H24FNO3
MW:
417.4720632
Mol File:
1817798-20-1.mol
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2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide Chemical Properties

Boiling point:
631.4±55.0 °C(Predicted)
Density 
1.211±0.06 g/cm3(Predicted)
storage temp. 
Room Temperature
solubility 
Chloroform, Dichloromethane, Dimethylsulfoxide, Methanol
pka
11.49±0.59(Predicted)
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2-(2-(3-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide Usage And Synthesis

Uses

3-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide is an intermediate in the synthesis of 3-Fluoro Atorvastatin Sodium Salt (F587915). 3-Fluoro Atorvastatin Sodium Salt is an impurity of Atorvastatin (A791750, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and the only drug in its class specifically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

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