Propargyl-PEG6-Ms
Propargyl-PEG6-Ms Basic information
- Product Name:
- Propargyl-PEG6-Ms
- Synonyms:
-
- Propargyl-PEG6-Ms
- Propargyl-PEG5-Ms
- PropargylPEG5Ms,PROTAC Linkers,Inhibitor,inhibit,Propargyl-PEG-5-Ms,Propargyl PEG5 Ms
- Propargyl-PEG5-Ms/3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol, 1-methanesulfonate
- 2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethyl methanesulfonate
- 3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol, 1-methanesulfonate
- CAS:
- 1036204-62-2
- MF:
- C14H26O8S
- MW:
- 354.42
- Mol File:
- 1036204-62-2.mol
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Propargyl-PEG6-Ms Chemical Properties
- Boiling point:
- 468.4±45.0 °C(Predicted)
- Density
- 1.171±0.06 g/cm3(Predicted)
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Propargyl-PEG6-Ms Usage And Synthesis
Description
Propargyl-PEG6-Ms is a PEG reagent that enables Click Chemistry reactions with azide-bearing compounds or biomolecules; copper is needed as a catalyst. The PEG spacer increases the water solubility of the reagent in aqueous environment.
Uses
Propargyl-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG6-MsSupplier
Sichuan Wei Keqi Biological Technology Co., Ltd.
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- 028-81700200 18116577057
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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Amatek Scientific Co. Ltd.
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- 0512-56316828
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Alfa Chemistry
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TargetMol Chemicals Inc.
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