CLOCORTOLONE PIVALATE Chemical Properties

Melting point:

231-233°C

Boiling point:

598.0±50.0 °C(Predicted)

Density 

1.24±0.1 g/cm3(Predicted)

storage temp. 

Refrigerator, under inert atmosphere

solubility 

Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)

pka

13.04±0.70(Predicted)

form 

Solid

color 

White

Safety Information

HS Code 

2937220000

CLOCORTOLONE PIVALATE Usage And Synthesis

Uses

Clocortolone Pivalate is a corticosteroid used in the treatment of atopic dermatitis.

Definition

ChEBI: The 21-O-pivalate ester of clocortolone. It is used for the relief of inflammatory and pruritic (itching) skin disorders.

brand name

Cloderm (Healthpoint).

General Description

Clocortolone pivalate, 9-chloro-21-(2,2-dimethyl-1-oxopropoxy)-6α-fluoro-11β-hydroxy-16α-methylpregna-1,4-diene-3,20-dione (Cloderm),along with desoximetasone, lacks the C17α oxygen functionalitythat is present in other GCs but still retains goodGC activity.

CLOCORTOLONE PIVALATE(34097-16-0)Related Product Information

• CLOCORTOLONE PIVALATE
• Clocortolone
• 2-CHLOROCYCLOHEXANOL
• trans-2-Chlorocyclohexanol
• 3-CHLORO-2,2,3-TRIMETHYLBUTANE