FAUC 213
FAUC 213 Basic information
- Product Name:
- FAUC 213
- Synonyms:
-
- Pyrazolo[1,5-a]pyridine, 2-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-
- inhibit,p5-HT2,FAUC 213,orally,pα1,BBB,AMPH,barrier,amphetamin,blood-brain,Inhibitor,Dopamine Receptor,p5-HT1,antipsychotic
- FAUC213 FAUC-213
- CAS:
- 337972-47-1
- MF:
- C18H19ClN4
- MW:
- 326.82
- Mol File:
- 337972-47-1.mol
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FAUC 213 Chemical Properties
- storage temp.
- 2-8°C
- solubility
- DMSO: ~24 mg/mL with warming up to 60°C
- form
- solid
- color
- white
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FAUC 213 Usage And Synthesis
Uses
FAUC 213 is a highly selective D4 dopamine receptor full antagonist.
in vivo
FAUC 213 (7.5-30 mg/kg; orally; single dose) significantly reduces this elevation in AMPH-induced locomotor hyper-activity only pre-treatment with 30 mg/kg. FAUC 213 significantly restores the prepulse inhibition (PPI) reduction caused by the apomorphine (APO) treatment with 30 mg/kg[1].
| Animal Model: | Male adult Wistar rats weighing 300-350 g[1] |
| Dosage: | 7.5, 15, 30 mg/kg |
| Administration: | Orally; single dose |
| Result: | Significantly reduced this elevation in amphetamin (AMPH)-induced locomotor hyper-activity only pre-treatment with 30 mg/kg. |
IC 50
hD4.4 Receptor: 2.2 nM (Ki); hD2 Receptor: 3.4 μM (Ki); hD3 Receptor: 5.3 μM (Ki)
FAUC 213Supplier
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai YuanYe Biotechnology Co., Ltd.
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- 021-61312847; 18021002903
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ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
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Shanghai Chaolan Chemical Technology Center
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- 021-QQ：65489617 15618227136
- Sales@ATKchemical.com
Chuzhou KeMail Chemical Technology Co., Ltd
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- 0550-5196001 15000891977
- wj520wjxby@126.com