Thioredoxin reductase peptide Chemical Properties

Boiling point:

1838.3±65.0 °C(Predicted)

Density 

1.302±0.06 g/cm3(Predicted)

pka

3.60±0.21(Predicted)

Sequence

Trp-Gly-Leu-Gly-Gly-Thr-Cys-Val-Asn-Val-Gly-Cys-Ile-Pro-Lys

Thioredoxin reductase peptide Usage And Synthesis

Uses

Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense[1][2].

References

[1] Jan YH, et al. Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine(methylbis(2-chloroethyl)amine) in human lung epithelial cells and rat lung: selective inhibition of disulfide reduction but not redox cycling. Chem Res To DOI:10.1021/tx400329a
[2] Valette O, et al. Biochemical Function, Molecular Structure and Evolution of an Atypical Thioredoxin Reductase from Desulfovibrio vulgaris. Front Microbiol. 2017 Sep 29;8:1855. DOI:10.3389/fmicb.2017.01855