N,N′-di-sec-butyl-N,N′-dinitroso-1,4-phenylenediamine
N,N′-di-sec-butyl-N,N′-dinitroso-1,4-phenylenediamine Basic information
- Product Name:
- N,N′-di-sec-butyl-N,N′-dinitroso-1,4-phenylenediamine
- Synonyms:
-
- N,N′-di-sec-butyl-N,N′-dinitroso-1,4-phenylenediamine
- BNN6
- 1,4-Benzenediamine, N1,N4-bis(1-methylpropyl)-N1,N4-dinitroso-
- CAS:
- 106476-75-9
- MF:
- C14H22N4O2
- MW:
- 278.35
- Mol File:
- 106476-75-9.mol
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N,N′-di-sec-butyl-N,N′-dinitroso-1,4-phenylenediamine Chemical Properties
- Boiling point:
- 462.7±41.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- pka
- -2.60±0.50(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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N,N′-di-sec-butyl-N,N′-dinitroso-1,4-phenylenediamine Usage And Synthesis
Uses
BNN6 is a thermoresponsive NO donor. BNN6 can be used to synthesize a multifunctional bio-transducer BNN6-BiTiS3-iRGD. BNN6-BiTiS3-iRGD can produce NO, arrest the cell cycle and induce apoptosis, and synergize with photothermal therapy (PTT) to ameliorate cancer[1].
References
[1] Jiang M, et al., BiTiS3 bio-transducer with explosive on-demand generation of NO gas for synergetic cancer therapy. Biosens Bioelectron. 2024 Feb 15;246:115895. DOI:10.1016/j.bios.2023.115895
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