THP-PEG9-OH
THP-PEG9-OH Basic information
- Product Name:
- THP-PEG9-OH
- Synonyms:
-
- THP-PEG9-OH
- OH-PEG9-THP
- THP-PEG9-OH/3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-[(tetrahydro-2H-pyran-2-yl)oxy]-
- 3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-[(tetrahydro-2H-pyran-2-yl)oxy]-
- CAS:
- 669556-83-6
- MF:
- C23H46O11
- MW:
- 498.6
- Mol File:
- 669556-83-6.mol
More
Less
THP-PEG9-OH Chemical Properties
- Boiling point:
- 569.2±50.0 °C(Predicted)
- Density
- 1.11±0.1 g/cm3(Predicted)
- pka
- 14.36±0.10(Predicted)
More
Less
THP-PEG9-OH Usage And Synthesis
Biological Activity
THP-PEG9-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
THP-PEG9-OHSupplier
Amatek Scientific Co. Ltd.
- Tel
- 0512-56316828
- info@amateksci.com
Xi'an Confluore Biological Technology Co., Ltd.
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
- Tel
- 15229059051
- 1027@dideu.com
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
- Tel
- 0431-80514535 19917294565
- et@chemextension.com