ChemicalBook > Product Catalog > Organic Chemistry > Carboxylic acids and derivatives > Abarelix (acetate)
Abarelix (acetate)
Abarelix (acetate) Basic information
- Product Name:
- Abarelix (acetate)
- Synonyms:
-
- N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-D-asparaginyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-D-alaninamide, acetate salt
- CAS:
- 785804-17-3
- MF:
- C74H99ClN14O16
- MW:
- 1476.14
- Mol File:
- 785804-17-3.mol
More
Less
Abarelix (acetate) Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 5 mg/ml
- form
- A crystalline solid
- color
- white to beige
More
Less
More
Less
Abarelix (acetate) Usage And Synthesis
Description
Abarelix acetate is a synthetic third generation gonadotropin-releasing hormone receptor (GnRHR) antagonist. It increases histamine release from rat peritoneal mast cells in vitro and from a human skin model ex vivo. In vivo, abarelix decreases plasma luteinizing hormone (LH) levels six hours post-treatment in castrated rats, with levels returning to baseline within 24 hours.3 Abarelix (2 mg/kg) also transiently decreases plasma testosterone levels in intact rats, with levels returning to baseline within seven days post-treatment. Formulations containing abarelix have previously been used in the treatment of advanced prostate cancer.
Abarelix (acetate)Supplier
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
- Tel
- 18818260767
- sales@chemegen.com
Beijing Biocreative Technology Co., Ltd.
- Tel
- 15522676233
- 3007606172@qq.com
Shanghai Yifei Biotechnology Co. , Ltd.
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
TargetMol Chemicals Inc.
- Tel
- 15002134094
- marketing@targetmol.cn