N1-Methyl ara-uridine Chemical Properties

Boiling point:

501.1±60.0 °C(Predicted)

Density 

1.605±0.06 g/cm3(Predicted)

pka

13.26±0.70(Predicted)

N1-Methyl ara-uridine Usage And Synthesis

Uses

N1-Methyl ara-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

N1-Methyl ara-uridine(17676-62-9)Related Product Information

• 8-Methyl-2'-deoxyadenosine
• 8-methyl-2'-deoxyguanosine