LY 231617
LY 231617 Basic information
- Product Name:
- LY 231617
- Synonyms:
-
- 2,6-bis(1,1-Dimethylethyl)-4-[(ethylamino)methyl]phenol hydrochloride
- LY 231617
- 2,6-BIS(1,1-DIMETHYLETHYL)-4-[[(1-ETHYL)AMINO]METHYL]PHENOL, HCL
- 2,6-di-tert-butyl-4-((ethylamino)methyl)phenol hydrochloride
- CAS:
- 141545-89-3
- MF:
- C17H30ClNO
- MW:
- 299.88
- Mol File:
- 141545-89-3.mol
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LY 231617 Chemical Properties
- storage temp.
- -20°C
- solubility
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- form
- Powder
- color
- Light yellow to yellow
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LY 231617 Usage And Synthesis
Uses
LY 231617 is an antioxidant and is able to prevent ischaemia-induced neurodegeneration. LY 231617 is a neuroprotective and an anti-ischaemic agent.
in vivo
LY231617 (50 mg/kg; p.o. 30 minutes before occlusion) reduces global ischemic neuronal injury in rats[2]. LY231617 (20 mg/kg; i.v. 30 minutes after occlusion) protects hippocampus and striatum from four-vessel occlusion[2].
| Animal Model: | Male Wistar rats four-vessel occlusion[2] |
| Dosage: | 50 mg/kg |
| Administration: | Oral gavage; 50 mg/kg 30 minutes before occlusion |
| Result: | Significantly protected both the hippocampus and striatum from 30 minutes of four-vessel occlusion. |
| Animal Model: | Male Wistar rats four-vessel occlusion[2] |
| Dosage: | 20 mg/kg |
| Administration: | Intravenous injection ; 20 mg/kg 30 minutes after occlusion |
| Result: | Significantly protected the hippocampus and the striatum when given 30 minutes after the onset of the ischemia at the time of reperfusion. |
LY 231617Supplier
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
MQ (shanghai) Pharmaceuticals Co., Ltd.
- Tel
- 13761635123
- 1014988033@qq.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
Energy Chemical
- Tel
- 021-58432009 400-005-6266
- marketing1@energy-chemical.com
MedBioPharmaceutical Technology Inc
- Tel
- 021-69568360 18916172912
- order@med-bio.cn
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