(S)-(+)-DIMETHINDENE MALEATE Chemical Properties

Boiling point:

416.3±45.0 °C(Predicted)

Density 

1.065±0.06 g/cm3(Predicted)

storage temp. 

Desiccate at RT

pka

9.58±0.28(Predicted)

InChI

InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3/t15-/m1/s1

InChIKey

MVMQESMQSYOVGV-OAHLLOKOSA-N

SMILES

C1C2=C(C=CC=C2)C([C@@H](C2=NC=CC=C2)C)=C1CCN(C)C

(S)-(+)-DIMETHINDENE MALEATE Usage And Synthesis

Uses

(S)-(+)-Dimethindene Maleate is a subtype-selective mAChR M2 antagonist and histamine H1 receptor antagonist.

Definition

ChEBI: N,N-dimethyl-2-[3-[(1S)-1-(2-pyridinyl)ethyl]-1H-inden-2-yl]ethanamine is an indene.

Biological Activity

Enantiomer that is a subtype-selective M 2 muscarinic receptor antagonist (pK i values are 7.08, 7.78, 6.70 and 7.00 for M 1 , M 2 , M 3 and M 4 receptors respectively). Also H 1 histamine receptor antagonist (pK i = 7.48).

(S)-(+)-DIMETHINDENE MALEATE(121367-05-3)Related Product Information

• Indene
• DIMETHINDENE
• (S)-(+)-DIMETHINDENE MALEATE
• DIMETHINDENE MALEATE