I-OME-AG 538
I-OME-AG 538 Basic information
- Product Name:
- I-OME-AG 538
- Synonyms:
-
- TYRPHOSTIN I-OME-AG 538
- I-OME-AG 538
- I-OME-TYRPHOSTIN AG 538
- ALPHA-CYANO-(3-METHOXY-4-HYDROXY-5-IODOCINNAMOYL)-(3',4'-DIHYDROXYPHENYL)KETONE
- I-OMe-AG 538, α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3μ,4μ-dihydroxyphenyl)ketone
- α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone
- IOMeTyrphostin AG 538,I OMe Tyrphostin AG 538
- I-OMe-Tyrphostin AG 538, 10 mM in DMSO
- CAS:
- 1094048-77-7
- MF:
- C17H12INO5
- MW:
- 437.19
- Mol File:
- Mol File
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I-OME-AG 538 Chemical Properties
- storage temp.
- -20°C
- solubility
- DMSO : 50 mg/mL (114.37 mM; Need ultrasonic)
- form
- solid
- color
- Yellow to orange
- InChI
- 1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+
- InChIKey
- HSRMHXWCTRFVHK-NYYWCZLTSA-N
- SMILES
- COc1cc(cc(I)c1O)\C=C(/C#N)C(=O)c2ccc(O)c(O)c2
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
MSDS
- Language:English Provider:SigmaAldrich
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I-OME-AG 538 Usage And Synthesis
Uses
I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.
Definition
ChEBI: 2-[(3,4-dihydroxyphenyl)-oxomethyl]-3-(4-hydroxy-3-iodo-5-methoxyphenyl)-2-propenenitrile is a member of chalcones.
Biochem/physiol Actions
Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.
I-OME-AG 538Supplier
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
TargetMol Chemicals Inc.
- Tel
- 4008200310
- marketing@tsbiochem.com
Shanghai Yifei Biotechnology Co. , Ltd.
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com