METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE Chemical Properties

Melting point:

141-142 °C

Boiling point:

382.2±22.0 °C(Predicted)

Density 

1.313±0.06 g/cm3(Predicted)

pka

11.26±0.40(Predicted)

METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE Usage And Synthesis

Uses

Methyl 7-Methoxy-2H-indazole-3-carboxylate is an intermediate in the synthesis of 7-Hydroxy Granisetron (H942675), a metabolite of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.

METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE(885278-95-5)Related Product Information

• METHYL 7-BENZYLOXY-1H-INDAZOLE-3-CARBOXYLATE
• ETHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
• 7-METHOXY-1H-INDAZOLE
• ETHYL 7-BENZYLOXY-1H-INDAZOLE-3-CARBOXYLATE
• 7-METHOXY-3-INDAZOLECARBOXYLIC ACID
• METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
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