Trimethylfluorosilane Chemical Properties

Melting point:

−74 °C(lit.)

Boiling point:

16 °C(lit.)

Density 

0.793 g/mL at 25 °C(lit.)

Flash point:

−22 °F

solubility 

sol most organic solvents

Specific Gravity

0.793

Hydrolytic Sensitivity

8: reacts rapidly with moisture, water, protic solvents

BRN 

1731132

CAS DataBase Reference

420-56-4(CAS DataBase Reference)

NIST Chemistry Reference

Silane, fluorotrimethyl-(420-56-4)

EPA Substance Registry System

Fluorotrimethylsilane (420-56-4)

Safety Information

Hazard Codes 

F+,Xi,F

Risk Statements 

12-36/37/38

Safety Statements 

9-16-26-33

RIDADR 

UN 1954 2.1

WGK Germany 

3

F 

4.5-9-21

Hazard Note 

Flammable

TSCA 

Yes

HazardClass 

2.1

HS Code 

2931900090

MSDS

• Language:English Provider:SigmaAldrich

Trimethylfluorosilane Usage And Synthesis

Chemical Properties

Clear liquid

Uses

Trimethylfluorosilane is used in the pharmaceutical and chemical industry.

Preparation

Trimethylfluorosilane can be prepared from Chlorotrimethylsilane (TMSCl) by direct treatment with Hydrofluoric Acid. It can also be generated in situ by reaction of Ethyl Trimethylsilylacetate (ETSA) and Tetra-n-butylammonium Fluoride (TBAF).

Reactions

Trimethylfluorosilane is capable of silylating ketones, alcohols, and terminal alkynes.

Purification Methods

It is a FLAMMABLE gas which is purified by fractional distillation through a column at low temperature and with the exclusion of air [Booth & Suttle J Am Chem Soc 68 2658 1946, Reid & Wilkins J Chem Soc 4029 1955]. [Beilstein 4 IV 4007.]

Trimethylfluorosilane(420-56-4)Related Product Information

• DIPHENYLMETHYLFLUOROSILANE
• 1,1,3,3-TETRAKIS(DIMETHYLAMINO)-2-AZOALLENE DIFLUORO(TRIMETHYL)SILICATE
• Trimethylfluorosilane
• VINYLDIMETHYLFLUOROSILANE
• ETHYLDIMETHYLFLUOROSILANE
• HEXAMETHYLGUANIDINIUM TRIMETHYLDIFLUORO SILICONATE
• Tetrabutylammonium Difluorotriphenylsilicate
• FLUOROTRIETHYLSILANE
• N-BUTYLDIMETHYLFLUOROSILANE
• TAS-F
• DIMETHYLPHENYLFLUOROSILANE
• CHLOROMETHYL-DIMETHYL-FLUOROSILANE
• TRIPHENYLFLUOROSILANE
• 3-AMINOPROPYLDIMETHYLFLUOROSILANE
• 2-DIMETHYLAMINO-1,3-DIMETHYLIMIDAZOLINIUM-TRIMETHYLDIFLUORO-SILICONATE
• FLUOROTRIBENZYL SILANE