BIS(3,5-DI-TERT-BUTYL-4-METHOXYPHENYL)CHLOROPHOSPHINE Chemical Properties

Melting point:

116-120 °C

Boiling point:

552.5±50.0 °C(Predicted)

form 

solid

Water Solubility 

Reacts with water.

Sensitive 

Air & Moisture Sensitive

InChI

1S/C30H46ClO2P/c1-27(2,3)21-15-19(16-22(25(21)32-13)28(4,5)6)34(31)20-17-23(29(7,8)9)26(33-14)24(18-20)30(10,11)12/h15-18H,1-14H3

InChIKey

VOGHMZHRQUWLRE-UHFFFAOYSA-N

SMILES

COc1c(cc(cc1C(C)(C)C)P(Cl)c2cc(c(OC)c(c2)C(C)(C)C)C(C)(C)C)C(C)(C)C

Safety Information

Hazard Codes 

F

Risk Statements 

11

RIDADR 

UN3261

WGK Germany 

3

HazardClass 

8

PackingGroup 

II

Storage Class

4.1B - Flammable solid hazardous materials

Hazard Classifications

Flam. Sol. 2

BIS(3,5-DI-TERT-BUTYL-4-METHOXYPHENYL)CHLOROPHOSPHINE Usage And Synthesis

Uses

It is used as a reactant for asymmetric hydrogenation with iridium catalysts, chemo selective reaction with deprotonated 2-hydoxy-3,3,N-trimethylbutanamide. It is also used as a reactant for synthesis of phosphine- containing amino acids and peptide-based catalyst ligands, nonracemic phosphine-containing amino acids for palladium- catalyzed asymmetric allylic substitution reactions.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

BIS(3,5-DI-TERT-BUTYL-4-METHOXYPHENYL)CHLOROPHOSPHINE(212713-08-1)Related Product Information

• Chlorodiphenylphosphine
• BIS(3,5-DIMETHYL-4-METHOXYPHENYL)PHOSPHINE
• BIS(4-METHOXYPHENYL)CHLOROPHOSPHINE
• BIS(3,5-DIMETHYLPHENYL)CHLOROPHOSPHINE
• BIS(3,5-DI-TERT-BUTYL-4-METHOXYPHENYL)CHLOROPHOSPHINE
• BIS(3,5-DIMETHYL-4-METHOXYPHENYL)CHLOROPHOSPHINE