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3-Pyrrolidinone

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3-Pyrrolidinone Basic information

Product Name:
3-Pyrrolidinone
Synonyms:
  • PYRROLIDIN-3-ONE
  • 3-PYRROLIDINONE
  • 3-PYRROLIDONE HCL
  • 3-Pyrrolidone
  • 3-PYRROLIDINONE,97%
  • 1H-3-PYRROLIDINONE HYDROCHLORIDE
  • 3-Pyrrolidinone hydrochlo...
  • 3-Oxopyrrolidine
CAS:
96-42-4
MF:
C4H7NO
MW:
85.1
Mol File:
96-42-4.mol
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3-Pyrrolidinone Chemical Properties

Boiling point:
156.0±23.0 °C(Predicted)
Density 
1.047±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka
7.42±0.20(Predicted)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-39
HS Code 
2914390090
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3-Pyrrolidinone Usage And Synthesis

Uses

3-Pyrrolidinones are synthetically versatiles substrate, as they can be used to synthesise a large variety of heterocyclic compounds, such as indoles and 5-deazapteroic acid analogues and as a raw material for drug synthesis. The high reactivity of an active methylene group next to the carbonyl of the pyrrolidine ring is helpful for various syntheses[1].

References

[1] Fathy Abdel-Kader Amer. “Synthesis and reactions of 3-pyrrolidinones.” Journal of Heterocyclic Chemistry 45 6 (2009): 1549–1569.

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