7-BROMO-2,4-DIAMINOQUINAZOLINE Chemical Properties

Boiling point:

509.4±58.0 °C(Predicted)

Density 

1.828±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

form 

Solid

pka

7.94±0.70(Predicted)

color 

White to off-white

Safety Information

HS Code 

2933499090

7-BROMO-2,4-DIAMINOQUINAZOLINE Usage And Synthesis

Uses

DHFR-IN-3 is a dihydrofolate reductase (DHFR) inhibitor with the IC50 values of 19 μM and 12 μM in rat liver and P. carinii DHFR, respectively[1].

References

[1] A Rosowsky, et al. Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase. Antimicrob Agents Chemother. 1995 Jan;39(1):79-86. DOI:10.1128/AAC.39.1.79

7-BROMO-2,4-DIAMINOQUINAZOLINE(137553-43-6)Related Product Information

• 2,4-DIAMINOQUINAZOLINE
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• 7-BROMO-2,4-DIAMINOQUINAZOLINE
• 2-Amino-7-bromoquinazoline