5-Methyl-1H-pyrazole-3-carboxylic acid Chemical Properties

Melting point:

241 °C

Boiling point:

388.8±22.0 °C(Predicted)

Density 

1.404±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in dimethyl sulfoxide.

form 

powder to crystal

pka

15.36±0.10(Predicted)

color 

White to Yellow to Orange

CAS DataBase Reference

402-61-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

RTECS 

UQ6407500

HazardClass 

IRRITANT

HS Code 

29331990

MSDS

• Language:English Provider:SigmaAldrich

5-Methyl-1H-pyrazole-3-carboxylic acid Usage And Synthesis

Chemical Properties

White to light yellow solid

Uses

3-Methylpyrazole-5-carboxylic acid is a potent and selective D-amino acid oxidase (DAO) (also known as DAAO, DAMOX and OXDA) inhibitor that protects DAO cells from oxidative stress induced by D-Serine. 3-Methylpyrazole-5-carboxylic acid specifically prevents formalin-induced tonic pain.

Definition

ChEBI: A memebr of the class of pyrazoles that is 1H-pyrazole with methyl and carboxylic acid group substituents at positions 5 and 3 respectively.

General Description

3-Methylpyrazole-5-carboxylic acid is a potent and selective D-amino acid oxidase (DAO) (also known as DAAO, DAMOX and OXDA) inhibitor that protects DAO cells from oxidative stress induced by D-Serine. 3-Methylpyrazole-5-carboxylic acid specifically prevents formalin-induced tonic pain.

5-Methyl-1H-pyrazole-3-carboxylic acid(402-61-9)Related Product Information

• 5-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID
• 1,5-DIMETHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID
• 5-Methyl-1H-pyrazole-3-carboxylic acid
• 1-ETHYL-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
• ETHYL 1,5-DIMETHYL-1H-PYRAZOLE-3-CARBOXYLATE
• Ethyl 3-methyl-1H-pyrazole-5-carboxylate
• 3,5-PYRAZOLEDICARBOXYLIC ACID MONOHYDRATE
• 1,3-Dimethylpyrazole-5-carboxylic acid
• 1-ETHYL-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
• 1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
• Ethyl 5-thien-2-yl-1H-pyrazole-3-carboxylate
• 3,5-PYRAZOLEDICARBOXYLIC ACID
• 4-BROMO-1-ETHYL-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID,4-BROMO-1-ETHYL-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
• 5-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-1-methyl-1h-pyrazole-4-carboxylic acid
• ETHYL 1-(TERT-BUTYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE
• ETHYL 5-(2-FURYL)-1-METHYL-1H-PYRAZOLE-3-CARBOXYLATE
• ETHYL 2-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE
• 3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID