BDP 564/570 carboxylic acid
BDP 564/570 carboxylic acid Basic information
- Product Name:
- BDP 564/570 carboxylic acid
- Synonyms:
-
- BDP 564/570 carboxylic acid
- BODIPY 564/570 carboxylic acid
- BODIPY 564/570 acid
- Borate(1-), difluoro[5-[[5-[(1E)-2-phenylethenyl]-2H-pyrrol-2-ylidene-κN]methyl]-1H-pyrrole-2-propanoato(2-)-κN1]-, hydrogen (1:1), (T-4)-
- 3-(5,5-Difluoro-7-styryl-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)propanoic acid
- CAS:
- 150173-89-0
- MF:
- C20H16BF2N2O2.H
- MW:
- 366.17
- Mol File:
- 150173-89-0.mol
BDP 564/570 carboxylic acid Chemical Properties
- solubility
- Soluble in DMF, DMSO, chlorinated organic solvents
- Appearance
- Dark brown solid
- ex/em
- 566/576 nm
- ε(extinction coefficient)
- 110000 L⋅mol−1⋅cm−1
- Φ(quantum yield)
- 0.74
BDP 564/570 carboxylic acid Usage And Synthesis
Description
BDP 564/570 is a fluorophore with the emission in the orange part of the spectrum. The dye is pretty hydrophobic. It can be used for the labeling of lipids, oligonucleotides, peptides, and many other large and small molecules.
Free carboxylic acid can be used in peptide synthesis as an N-terminal monomer. An NHS ester with a pre-activated carboxy group is also available.
Chemical Properties
Appearance: Dark brown solid
ex/em: 566/576 nm
Extinction coefficient (ε): 110000 L??mol??1??cm??1
Quantum yield (Φ): 0.74
Uses
BODIPY 564/570 is a fluorescent dye that can be used in labeling superparamagnetic nanoparticles (MNPs). BODIPY 564/570 exhibits a maximal excitation wavelength of 564 nm and a maximal emission wavelength of 570 nm[1].
References
[1] Polyak B, et al., High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):698-703. DOI:10.1073/pnas.0708338105
Abs/Em Maxima
565/574 nm
Fluoresene quantum yield
0.74
Extinction Coefficient
110000
CF260
0.01
CF280
0.03
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