cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol Chemical Properties

Melting point:

126-129°C

Boiling point:

519.4±60.0 °C(Predicted)

Density 

1.52g/cm3 at 20℃

vapor pressure 

0-0Pa at 20-25℃

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

14.20±0.10(Predicted)

color 

White to Off-White

LogP

1.7 at pH7

cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol Usage And Synthesis

Uses

cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol is an Itraconazole(I937500) Intermediate. Itraconazole(I937500) is an orally active antimycotic structurally related to Ketoconazol.

cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol (67914-85-6)Related Product Information

• cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate
• Itraconazole Impurity 15
• cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl methanesulphonate
• (1,2,4-Triazol-4-yl) Itraconazole
• 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
• HYDROXY ITRACONAZOLE
• Propyl Itraconazole
• 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE
• Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole
• cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl benzoate
• Itraconazole
• 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine
• 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-
• KETO ITRACONAZOLE
• Butyl Itraconazole
• Itraconazole Impurity 34
• N-Desalkyl Itraconazole
• trans-Itraconazole