chloralodol
chloralodol Basic information
- Product Name:
- chloralodol
- Synonyms:
-
- chloralodol
- Chlorhexadol
- 2-Methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)-2-pentanol
- Lora
- Mecoral
- Medodorm
- 2-methyl-4-(2,2,2-trichloro-1-hydroxy-ethoxy)pentan-2-ol
- 2-methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)pentan-2-ol
- CAS:
- 3563-58-4
- MF:
- C8H15Cl3O3
- MW:
- 265.56
- EINECS:
- 222-634-9
- Mol File:
- 3563-58-4.mol
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chloralodol Chemical Properties
- Melting point:
- 102-104°
- Boiling point:
- 304.7±37.0 °C(Predicted)
- Density
- 1.348±0.06 g/cm3(Predicted)
- pka
- 10.73±0.20(Predicted)
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chloralodol Usage And Synthesis
Originator
Chloralodol,Shanghai Lancheng Corporation
Uses
Mechloral is a hypnotic/sedative.
Definition
ChEBI: Chloralodol is a tertiary alcohol.
Manufacturing Process
472 g of 2-methyl-2,4-pentanediol (4 moles) are heated to 70°-80°C in a bowl, and 660 g of chloral hydrate (4 moles) are added under stirring until all of chloral hydrate is dissolved. The temperature, which decreases during the addition, then increased to 60° to 70°C. When reaction mixture has become a nearly dry crystal powder, the powder is subjected to further drying by slight heating. Yield of raw product is about 1060 g. Recrystallization is carried out from tetrachloromethane, and the yield is 980 g (about 92 %).
brand name
Lora (Wallace).
Therapeutic Function
Hypnotic