MELOXICAM SODIUM SALT HYDRATE Chemical Properties

storage temp. 

room temp

solubility 

DMSO: soluble5mg/mL, clear

color 

light yellow to dark yellow

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

26

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

MELOXICAM SODIUM SALT HYDRATE Usage And Synthesis

Uses

Meloxicam sodium salt hydrate has been used:

• as a cyclooxygenase-2 (COX-2) inhibitor in solid Ehrlich tumor
• as an alternative to diclofenac nonsteroidal anti-inflammatory drugs (NSAID) to treat vultures
• as a reference standard in liquid chromatography electrospray ionisation mass spectrometry (LC-ESI/MS)
• to test its effect on prostaglandin (PGE2) production in lipopolysaccharide (LPS)-induced COX-2 protein expression in RAW246.7 cells

Biochem/physiol Actions

Meloxicam, a member of the oxicam family, is a non-steroidal anti-inflammatory drug (NSAID). It is synthesized from piroxicam with aryl and the pyridyl ring substitution. Meloxicam is a cyclooxygenase-2 (COX-2) inhibitor, it may be useful in treating inflammation and pain. Meloxicam has been shown to stop thymulin-induced increas in concentration of cytokines and Nerve growth factor?(NGF) in the liver of rats. Meloxicam also suppresses tumor growth and may be capable of antagonizing cachexia?in vitro. It promotes apoptosis in hepatocellular carcinoma.

MELOXICAM SODIUM SALT HYDRATE(71125-39-8)Related Product Information

• Meloxicam