3-Isoxazolecarboxamide, 5-(2-furanyl)-N-[2-(1H-pyrazol-1-yl)ethyl]- Chemical Properties

Boiling point:

533.9±50.0 °C(Predicted)

Density 

1.42±0.1 g/cm3(Predicted)

storage temp. 

4°C, protect from light

solubility 

DMSO : 50 mg/mL (183.65 mM; Need ultrasonic)

form 

Solid

pka

13.13±0.46(Predicted)

color 

White to off-white

3-Isoxazolecarboxamide, 5-(2-furanyl)-N-[2-(1H-pyrazol-1-yl)ethyl]- Usage And Synthesis

Biological Activity

Wnt/β-catenin agonist 2 is a potent Wnt agonist. Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and can be used in the research of diseases related to the signal transduction[1]. (From patent WO2007078113A1, compound 39) Wnt/β-catenin agonist 2 is a activator for β-Catenin in SW480 cell line. Wnt/β-catenin agonist 2 shows effect on differentiation ST2 Cell into osteoblasts[1].

References

[1]. Jeong Woo Cho, et al. Isoxazole derivatives and use thereof. WO2007078113A1.

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