ENISOPROST
ENISOPROST Basic information
- Product Name:
- ENISOPROST
- Synonyms:
-
- SC-34301
- ENISOPROST
- Prosta-4,13-dien-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (4Z,11alpha,13E)-(+-)-
- Prosta-4,13-dien-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (4Z,11α,13E)-(±)-
- CAS:
- 81026-63-3
- MF:
- C22H36O5
- MW:
- 380.52
- Mol File:
- 81026-63-3.mol
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ENISOPROST Chemical Properties
- Boiling point:
- 490.2±45.0 °C(Predicted)
- Density
- 1.092±0.06 g/cm3(Predicted)
- pka
- 13.90±0.60(Predicted)
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ENISOPROST Usage And Synthesis
Uses
Anti-ulcerative.
Uses
Enisoprost is the antisecretory prostaglandin derivative. Analogue of Prostaglandin E1 (P838600), which is the primary prostaglandin that is easily crystallized from purified biological extracts.
in vivo
SC 34301 (200 μg/kg; p.o.; once a day for three days) significantly reduces bacterial translocation and improves survival[1].
| Animal Model: | BALB/c mice (E. coli, burned)[1] |
| Dosage: | 200 μg/kg |
| Administration: | P.o.; once a day for three days |
| Result: | Significantly reduced the degree of bacterial translocation as measured by blood dpm counts, improved survival rate to 60% in burned mice. |