(S)-3-N-CBZ-AMINO-SUCCINIMIDE
(S)-3-N-CBZ-AMINO-SUCCINIMIDE Basic information
- Product Name:
- (S)-3-N-CBZ-AMINO-SUCCINIMIDE
- Synonyms:
-
- (S)-benzyl 2,5-dioxopyrrolidin-3-ylcarbamate
- Carbamic acid, [(3S)-2,5-dioxo-3-pyrrolidinyl]-, phenylmethyl ester (9CI)
- CAS:
- 60846-91-5
- MF:
- C12H12N2O4
- MW:
- 248.23
- Mol File:
- 60846-91-5.mol
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(S)-3-N-CBZ-AMINO-SUCCINIMIDE Chemical Properties
- Boiling point:
- 515.1±49.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
- form
- A crystalline solid
- pka
- 8.79±0.50(Predicted)
- color
- White to off-white
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(S)-3-N-CBZ-AMINO-SUCCINIMIDE Usage And Synthesis
Uses
(S)-3-N-Cbz-Amino-succinimide (Compound 1d) is an antiepileptic agent that can inhibit pentylenetetrazole (PTZ) and maximal electroshock (MES)-induced tonic convulsions in mice[1].
References
[1] Lee J, et al. Synthesis and anticonvulsant evaluation of A series of (R)-and (S)-N-Cbz-α-aminosuccinmide and their structure activity relationship[J]. Archives of Pharmacal Research, 1996, 19: 312-316.
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