Basic information Safety Supplier Related

Divaplon

Basic information Safety Supplier Related

Divaplon Basic information

Product Name:
Divaplon
Synonyms:
  • Divaplon
  • (6-Ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)phenylmethanone
  • RU-32698
  • Methanone, (6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl-
CAS:
90808-12-1
MF:
C17H17N3O2
MW:
295.34
Mol File:
90808-12-1.mol
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Divaplon Usage And Synthesis

Uses

Divaplon is a GABA receptor agonist with the EC50 values of 31 and 2 nM for α3β2γ2 and α5β2γ2, respectively. Divaplon shows anxiolytic activity[1][2].

References

[1] Knoflach F, et al. Full and partial agonism displayed by benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes. J Pharmacol Exp Ther. 1993;266(1):385-391. PMID:8392559
[2] Sanger DJ, et al. Benzodiazepine (omega) receptor partial agonists and the acquisition of conditioned fear in mice. Psychopharmacology (Berl). 1995;121(1):104-108. DOI:10.1007/BF02245596

DivaplonSupplier

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