Ipenoxazone
Ipenoxazone Basic information
- Product Name:
- Ipenoxazone
- Synonyms:
-
- (4S,5R)-3-[3-(Hexahydro-1H-azepin-1-yl)propyl]-4-(2-methylpropyl)-5-phenyl-2-oxazolidinone
- Ipenoglan
- NC-1200
- Ipenoxazone
- MLV 6976
- 2-Oxazolidinone, 3-[3-(hexahydro-1H-azepin-1-yl)propyl]-4-(2-methylpropyl)-5-phenyl-, (4S,5R)-
- CAS:
- 104454-71-9
- MF:
- C22H34N2O2
- MW:
- 358.52
- Mol File:
- 104454-71-9.mol
Ipenoxazone Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
Ipenoxazone Usage And Synthesis
Uses
Ipenoxazone is a muscle relaxant. It acts on the brainstem or in the peripheral nervous system to reduce the excessive activities of the nervous system.
in vivo
Ipenoxazone is a potent and centrally acting muscle relaxant[1]. An intravenous injection of 2 mg/kg Ipenoxazone causes a reduction of electromyographic activity which reaches a maximum within 3 min after the injection. Within 1 min after the injection of Ipenoxazone at a dose of 4 mg/kg, the blood pressure changes from a control level of 138±9 mmHg to a minimum level of 98±9 mmHg (n=6) but it rapidly returns to the control level within 1 to 2 min, while the rigidity is still reduced significantly at that time. High doses (greater than 30 mg/kg i.p.) of Ipenoxazone produces a transient and dose-dependent sedation in almost all mice about 5 min after its administration[2].
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