Lesopitron
Lesopitron Basic information
- Product Name:
- Lesopitron
- Synonyms:
-
- Lesopitron
- Lesopitron, 10 mM in DMSO
- CAS:
- 132449-46-8
- MF:
- C15H21ClN6
- MW:
- 320.826
- Mol File:
- 132449-46-8.mol
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Lesopitron Usage And Synthesis
Uses
Lesopitron (E-4424) is a 5-HT receptor agonist with potent anxiolytic-like effects. Lesopitron inhibits forskolin-stimulated adenylate cyclase activity with an IC50 value of 125 nM[1].
References
[1] S Haj-Dahmane, et al. Interactions of lesopitron (E-4424) with central 5-HT1A receptors: in vitro and in vivo studies in the rat. Eur J Pharmacol. 1994. DOI:10.1016/0014-2999(94)90097-3
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