Tropatepine Chemical Properties

Boiling point:

493.1±45.0 °C(Predicted)

Density 

1.190±0.06 g/cm3(Predicted)

pka

10.59±0.20(Predicted)

form 

Solid

color 

White to off-white

Tropatepine Usage And Synthesis

Uses

Tropatepine is an orally active, anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic agents[2].

References

[1] P Celsis, et al. Effect of tropatepine, an anticholinergic drug, on regional cerebral blood flow in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1989 Jul;52(7):917-8. DOI:10.1136/jnnp.52.7.917
[2] P Arnoux, et al. Simultaneous determination of tropatepine and its major metabolites by high-performance liquid chromatographic-mass spectrometric identification. Application to metabolic and kinetic studies. J Chromatogr. 1986 Aug 22;381(1):75-82. PMID:3771726

Tropatepine(27574-24-9)Related Product Information

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