UK 55444
UK 55444 Basic information
- Product Name:
- UK 55444
- Synonyms:
-
- UK 55444
- Reaxys ID: 3640038
- 2-[2-[(2-Amino-4,5-dihydro-4-oxo-1H-imidazol)-1-yl]ethoxymethyl]-4-(2,3-dichlorophenyl)-1,4-dihydro-6-methylpyridine-3,5-dicarboxylic acid 3-ethyl 5-methyl ester
- 3,5-Pyridinedicarboxylic acid, 2-[[2-(2-amino-4,5-dihydro-4-oxo-1H-imidazol-1-yl)ethoxy]methyl]-4-(2,3-dichlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
- CAS:
- 97290-20-5
- MF:
- C23H26Cl2N4O6
- MW:
- 525.38
- Mol File:
- 97290-20-5.mol
More
Less
UK 55444 Chemical Properties
- Boiling point:
- 638.3±65.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- pka
- 5.96±0.20(Predicted)
More
Less
UK 55444 Usage And Synthesis
Description
UK 55444 is a potent (IC50 = 8 x 10(-9) M) calcium antagonist which is 40-fold selective for vascular over cardiac tissue and which has a significantly longer duration of action (greater than 3 h) than nifedipine in the anesthetized dog on intravenous administration.